Identification of HLA-B*56 variant (B*560502) in the Korean population
| Autor: | Han H, Kim Tg, Kim Cc, Chul-Woo Pyo, Kim Dw, Hur Ss |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Immunology
Molecular Sequence Data Biology Biochemistry Exon Genetics Immunology and Allergy Humans Point Mutation Nucleotide Typing Allele Alleles chemistry.chemical_classification Korea Base Sequence Korean population Haplotype General Medicine Exons Molecular biology HLA-B Amino acid Protein Structure Tertiary chemistry Haplotypes HLA-B Antigens Sequence Alignment |
| Zdroj: | Tissue antigens. 63(4) |
| ISSN: | 0001-2815 |
| Popis: | We report here a new HLA-B*56 allele, B*560502, identified by sequencing-based typing in the Korean population. HLA-B*560502 differs from B*560501 by a single nucleotide at position 141 in exon 2 (T(r)C). This single nucleotide substitution may not result in an amino acid difference in the alpha1 domain at residue 23. The putative haplotype involving B*560502 may be A*24-DRB1*1201-DQA1*0503-DQB1*0304-DPB1*0202. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text