Comparison of renal function between normal-weight and overweight children
Autor: | Behnaz Falakaflaki, A Moradzade, Saeideh Mazloomzadeh |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
Creatinine
medicine.medical_specialty kidney business.industry Renal function Urine Overweight medicine.disease chemistry.chemical_compound Endocrinology Blood pressure chemistry Nephrology Diabetes mellitus Internal medicine Albuminuria Medicine overweight Original Article medicine.symptom business Children Kidney disease |
Zdroj: | Indian Journal of Nephrology |
ISSN: | 1998-3662 0971-4065 |
Popis: | Obesity in children is associated with hypertension, dyslipidemia, cardiovascular disease, diabetes mellitus, colon cancer, and kidney disease. Most of the studies that evaluate the association between obesity and kidney disease have been done in adults. This study was planned to compare renal function between normal-weight and overweight children. In this case-control study, 92 children (45 boys, 47 girls) aged 7-12 years were included in the analysis. 46 children (23 boys, 23 girls) with BMI 85 th percentile or greater (mean age, 9.09 years) were compared with 46 controls (22 boys, 24 girls) with BMI 5 th -84 th percentile (mean age, 8.63 years). Blood and urine sample were taken from case and control groups. Urine albumin/creatinine ratio and urine calcium/creatinine ratio and glomerular filtration rate (GFR) were determined. Children in the overweight and control groups were matched according to age and sex. Glomerular filtration rate, urine calcium/creatinine ratio, urine albumin/creatinine ratio, blood pressure, and serum creatinine were compared between normal-weight and overweight children. Our finding showed no significant difference regarding GFR, albuminuria, calciuria, blood pressure, and serum creatinine between normal-weight and overweight children. |
Databáze: | OpenAIRE |
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