Genome-wide association and pathway analysis of carcass and meat quality traits in Piemontese young bulls
| Autor: | Alberto Brugiapaglia, Simone Savoia, Giovanni Bittante, Alfredo Pauciullo, Sara Pegolo, Alessio Cecchinato, A. Albera, L. Di Stasio |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Genotype Color Genome-wide association study Single-nucleotide polymorphism Biology Beef cattle Breeding SF1-1100 Polymorphism Single Nucleotide Linkage Disequilibrium functional analysis Piedmontese Animals Gene Genetics Autosome Genome double-muscled food and beverages Chromosome Mapping Genomics beef Breed Animal culture Condensin I complex Red Meat Phenotype genomic analysis Animal Science and Zoology Cattle Genome-Wide Association Study |
| Zdroj: | Animal, Vol 14, Iss 2, Pp 243-252 (2020) |
| ISSN: | 1751-732X |
| Popis: | A key concern in beef production is how to improve carcass and meat quality traits. Identifying the genomic regions and biological pathways that contribute to explaining variability in these traits is of great importance for selection purposes. In this study, genome wide-association (GWAS) and pathway-based analyses of carcass traits (age at slaughter (AS), carcass weight (CW), carcass daily gain (CDG), conformation score and rib-eye muscle area) and meat quality traits (pH, Warner-Bratzler shear force, purge loss, cooking loss and colour parameters (lightness, redness, yellowness, chroma, hue)) were conducted using genotype data from the ‘GeneSeek Genomic Profiler Bovine LD’ array in a cohort of 1166 double-muscled Piemontese beef cattle. The genome wide-association analysis was based on the GRAMMAR-GC approach and identified 37 significant single nucleotide polymorphisms (SNPs), which were associated with 12 traits (P |
| Databáze: | OpenAIRE |
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