Formulation and optimization of desogestrel transdermal contraceptive patch using crystallization studies
| Autor: | Ajay K. Banga, Agis Kydonieus, Yun Bai, Vishal Sachdeva |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
Pyrrolidines Vinyl Compounds Transdermal patch Skin Absorption Rats Hairless Transdermal Patch Pharmaceutical Science Levonorgestrel Pharmacology law.invention Excipients chemistry.chemical_compound law Desogestrel Adhesives medicine Animals Mineral Oil Crystallization Mineral oil Transdermal Acrylate Chromatography Chemistry Reproducibility of Results Contraceptives Oral Synthetic Rats Solubility Adhesive medicine.drug |
| Zdroj: | International Journal of Pharmaceutics. 441:9-18 |
| ISSN: | 0378-5173 |
| Popis: | Levonorgestrel (LNG) is the most commonly used progestin in contraception. In this study we report the use of an alternative progestin desogestrel for transdermal contraception. The drug was found to be significantly more permeable as compared to LNG (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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