Stereochemistry of Lignans in Phaleria macrocarpa (Scheff.) Boerl

Autor: A. Wilhelm Alfermann, Ahmad Saufi, Elisabeth Fuss, Cosima B. I. von Heimendahl
Rok vydání: 2008
Předmět:
Zdroj: Zeitschrift für Naturforschung C. 63:13-16
ISSN: 1865-7125
0939-5075
DOI: 10.1515/znc-2008-1-203
Popis: Phaleria macrocarpa (Scheff.) Boerl., a member of the Thymelaeaceae, is traditionally used in Indonesia as medicinal plant against cancer. In this context, we isolated the lignans pinoresinol, lariciresinol and matairesinol from different parts of this plant. The enantiomeric composition of these lignans was determined by chiral column analysis. Pinoresinol and lariciresinol were mixtures of both enantiomers with (79 ± 4)% and (55 ± 6)% enantiomeric excess for the (−)-enantiomers, respectively, whereas matairesinol was found as pure (+)-enantiomer.
Databáze: OpenAIRE