Acute intermittent porphyria (AIP) in a patient with celiac disease
| Autor: | Mathias Mäurer, Petra Budig, Christoph Uibel, Sebastian Nunnemann |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
030213 general clinical medicine
medicine.medical_specialty Pediatrics Neurology Context (language use) Disease macromolecular substances Neurological rehabilitation lcsh:RC346-429 lcsh:RC321-571 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Polyneuropathy medicine Acute intermittent porphyria Celiac disease lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Letter to the Editor lcsh:Neurology. Diseases of the nervous system business.industry nutritional and metabolic diseases Heme arginate medicine.disease Neurologic manifestation chemistry Neurosurgery business 030217 neurology & neurosurgery |
| Zdroj: | Neurological Research and Practice Neurological Research and Practice, Vol 2, Iss 1, Pp 1-2 (2020) |
| ISSN: | 2524-3489 |
| Popis: | We present the case of an 18 year old Caucasian with known celiac disease, who suffered a severe first attack of acute intermittent porphyria (AIP) with neuropsychiatric symptoms, severe tetraparesis and respiratory insufficiency. Treatment with heme arginate and high-dose intravenous glucose and rigorous rehabilitation resulted in a slow but almost complete recovery of her motor symptoms. To our knowledge this is the first case of acute intermittent porphyria triggered by malnutrition in the context of celiac disease. It is remarkable that the patient showed a favourable outcome despite the severity of her initial symptoms. This case shows the importance of early and systematic symptomatic treatment in patients with severe neurologic manifestation of AIP. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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