A report on the consequences of the first implanted device for long-term analgesia in refractory cancer pain
| Autor: | Sanjeet Narang, Robert N. Pilon, Sukumar P. Desai |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Attitude of Health Personnel Analgesic 03 medical and health sciences 0302 clinical medicine Patient satisfaction Lumbar Ommaya reservoir Medicine Humans Pain Management Anesthetics Local business.industry Local anesthetic Drug Administration Routes Cancer Pain Middle Aged Epidural space Surgery Pain Intractable Analgesia Epidural Anesthesiology and Pain Medicine medicine.anatomical_structure Treatment Outcome Patient Satisfaction 030220 oncology & carcinogenesis Anesthesia Intractable pain Female business Cancer pain Attitude to Health 030217 neurology & neurosurgery |
| Zdroj: | Journal of clinical anesthesia. 32 |
| ISSN: | 1873-4529 |
| Popis: | Background During the early 1970s, satisfactory long-term treatment of the severe pain associated with metastatic cancer was not available. Spinal cord stimulation introduced a few years earlier in 1967 had not proven to be effective in treating nociceptive pain. We describe our pioneering experience using an implanted device to infuse local anesthetics into the epidural space and provide pain relief to the patient. Methods Increasing doses of systemic opioids were unsuccessful in treating the intractable pain of spinal metastases in our patient. We devised an analgesic delivery system by modifying equipment usually used for ventriculoperitoneal shunts. A lumbar epidural catheter was inserted in the patient's spine, then tunneled subcutaneously across the flank to the anterior abdominal wall, and subsequently connected to a modified Ommaya reservoir with ventriculoperitoneal shunt tubing. This was filled with local anesthetic and injected into the patient's epidural space by manual compression. Results The system was used for several months with intermittent addition of local anesthetic to the reservoir with satisfactory control of the patient's pain. Conclusions We describe the first use of an implanted epidural catheter system for long-term relief of pain due to terminal cancer that occurred at Peter Bent Brigham Hospital in Boston. We contend that this event played an important role in the cascade of devices that followed and connect it to the changes in the attitude of health care providers toward treatment of cancer pain. |
| Databáze: | OpenAIRE |
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