Intestinal absorption of insulin in patients with fibrocystic disease
| Autor: | Edward M. Sewell, Robert Kaye, Marion J. Balsam, Philip G. Holtzapple |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Adolescent Cystic Fibrosis medicine.medical_treatment Fatty Acids Nonesterified Intestinal absorption Internal medicine medicine Humans Insulin In patient Child Pancreas Pancreatic Proteolytic Enzymes business.industry Human gastrointestinal tract Fibrocystic disease Endocrinology medicine.anatomical_structure Intestinal Absorption Pediatrics Perinatology and Child Health sense organs Insulin absorption business Peptide Hydrolases Plasma free fatty acid |
| Zdroj: | The Journal of Pediatrics. 79:1011-1014 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(71)80202-0 |
| Popis: | Summary Patients with fibrocystic disease were studied in an effort to determine the extent of intestinal absorption of insulin in human subjects who lack pancreatic proteolytic enzymes. Crystalline insulin was administered intraduodenally. Resultant changes in blood glucose, plasma free fatty acids, and plasma insulin levels suggest that pancreatic enzymes do play a role in preventing insulin absorption from the human gastrointestinal tract. When considered in light of the quantity of insulin administered, however, the changes in these parameters are relatively small. This suggests that other factors may be more important in contributing to the apparent resistance to insulin absorption under these circumstances. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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