High performance inkjet printed embedded electrochemical sensors for monitoring hypoxia in a gut bilayer microfluidic chip

Autor: Muhammad Asad Ullah Khalid, Kyung Hwan Kim, Abdul Rahim Chethikkattuveli Salih, Kinam Hyun, Sung Hyuk Park, Bohye Kang, Afaque Manzoor Soomro, Muhsin Ali, Yesl Jun, Dongeun Huh, Heeyeong Cho, Kyung Hyun Choi
Rok vydání: 2022
Předmět:
Zdroj: Lab on a chip. 22(9)
ISSN: 1473-0189
Popis: Sensing devices have shown tremendous potential for monitoring state-of-the-art organ chip devices. However, challenges like miniaturization while maintaining higher performance, longer operating times for continuous monitoring, and fabrication complexities limit their use. Herein simple, low-cost, and solution-processible inkjet dispenser printing of embedded electrochemical sensors for dissolved oxygen (DO) and reactive oxygen species (ROS) is proposed for monitoring developmental (initially normoxia) and induced hypoxia in a custom-developed gut bilayer microfluidic chip platform for 6 days. The DO sensors showed a high sensitivity of 31.1 nA L mg
Databáze: OpenAIRE