Neurodevelopmental outcome in children born to mothers wit hypertension in pregnancy: the significance of suboptimal intrauterine growth
| Autor: | Sarah Raz, Craig J. Sander, Mindy E. Kronenberg |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Fetus Pediatrics medicine.medical_specialty Fetal Growth Retardation business.industry Developmental Disabilities Hypertension in Pregnancy Gestational age Hypertension Pregnancy-Induced Pregnancy Complications Continuous variable Developmental Neuroscience Pregnancy Child Preschool Pediatrics Perinatology and Child Health Humans Medicine Female Neurology (clinical) Risk factor business |
| Zdroj: | Developmental Medicine & Child Neurology. 48:200-206 |
| ISSN: | 0012-1622 |
| DOI: | 10.1017/s0012162206000430 |
| Popis: | In this investigation of 45 children born to mothers with hypertension in pregnancy, our objective was to examine the role of a fetal risk factor (suboptimal intrauterine growth [SOIUG]) in determining developmental outcome. There were two groups of children: Group 1 (n=26; 10 males, 16 females; mean testing age 56.77 mo [SD 13.03], range 41-82 mo; mean gestational age 32.96 wks [SD 2.24], range 27-38 wks; mean birthweight 1,984.42g [SD 563], range 1,046-3,515g) without, and Group 2 (n=19; 6 males, 13 females; mean testing age 57.63 mo [SD 14.86], range 40-84 mo; mean gestational age 34.21 wks [SD 2.10], range 29-39 wks, mean birthweight 1,572g [SD 365], range 855-2,690g) with SOIUG. We found that SOIUG was associated with a significant reduction in cognitive and motor skills (p0.05). Visuospatial (p0.01) as well as motor skills (p0.001) were linearly associated with the extent of intrauterine growth deficit when the latter was treated as a continuous variable. To conclude, an increase in intrauterine growth deficit is accompanied by a proportionate decline in quality of developmental outcome in children born to mothers with hypertension in pregnancy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text