Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series
Autor: | Gilles Houvenaeghel, V. Moutardier, V. J. Bardou, M. Martino, Bernard Lelong, J. R. Delpero, Michel Resbeut |
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Rok vydání: | 2004 |
Předmět: |
Adult
medicine.medical_specialty Palliative care medicine.medical_treatment Uterine Cervical Neoplasms Salvage therapy medicine Humans Cervix Survival analysis Aged Retrospective Studies Cervical cancer Pelvic exenteration business.industry Mortality rate Palliative Care Obstetrics and Gynecology Retrospective cohort study Middle Aged Prognosis medicine.disease Survival Analysis Surgery medicine.anatomical_structure Oncology Female Neoplasm Recurrence Local business |
Zdroj: | International Journal of Gynecological Cancer. 14:846-851 |
ISSN: | 1525-1438 1048-891X |
DOI: | 10.1111/j.1048-891x.2004.14519.x |
Popis: | Pelvic recurrence of cervical cancer is a life-threatening situation and only local control can provide hope for remission. The aim of this study was to evaluate the role of surgery in the treatment of cervical cancer recurrence. This retrospective study analyzed a series of 70 patients who underwent resection of cervix locoregional recurrence. Thirteen patients had palliative salvage surgery for pelvic complications. Twenty-nine resections were considered as curative. Fifty recurrences required pelvic exenterations. The hospital mortality rate was 9% and the morbidity rate was 44%. Overall 5-year actuarial survival rate was 23%. Survival was significantly higher: (a) after curative resection and (b) after centropelvic recurrence resection. Local control was obtained in 48% of the cases and 13 patients are alive with a median follow-up of 75 months. In conclusion, the results of this small and heterogen series seem to justify an attempt to resection for centropelvic recurrences whenever possible. Palliative surgery should be reserved to salvage therapy and highly selected patients. |
Databáze: | OpenAIRE |
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