Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
| Autor: | Federico Perosa, Elvira Favoino, Maria Luisa Scarasciulli, Anna M. Colacicco, Angela Stufano, Paola Mascia, Paolo Romita, Caterina Foti, Chiara Barlusconi, Piero Lovreglio, Agata Calvario, Hamidreza Jahantigh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
business.industry T cell ELISPOT Case Report Infectious and parasitic diseases RC109-216 T cell response medicine.disease_cause Herpesviridae Valaciclovir Infectious Diseases medicine.anatomical_structure Enzyme chemistry Cutaneous Leukocytoclastic Vasculitis hemic and lymphatic diseases Immunology Medicine business Pathological medicine.drug |
| Zdroj: | IDCases, Vol 26, Iss, Pp e01331-(2021) IDCases |
| ISSN: | 2214-2509 |
| Popis: | Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response. |
| Databáze: | OpenAIRE |
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