Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases

Autor: Hollingsworth, T Déirdre, Adams, Emily R, Anderson, Roy M, Atkins, Katherine, Bartsch, Sarah, Basáñez, María-Gloria, Behrend, Matthew, Blok, David J, Chapman, Lloyd AC, Coffeng, Luc, Courtenay, Orin, Crump, Ron E, de Vlas, Sake J, Dobson, Andy, Dyson, Louise, Farkas, Hajnal, Galvani, Alison P, Gambhir, Manoj, Gurarie, David, Irvine, Michael A, Jervis, Sarah, Keeling, Matt J, Kelly-Hope, Louise, King, Charles, Lee, Bruce Y, Le Rutte, Epke A, Lietman, Thomas M, Ndeffo-Mbah, Martial, Medley, Graham F, Michael, Edwin, Pandey, Abhishek, Peterson, Jennifer K, Pinsent, Amy, Porco, Travis C, Richardus, Jan Hendrik, Reimer, Lisa, Rock, Kat S, Singh, Brajendra K, Stolk, Wilma, Swaminathan, Subramanian, Torr, Steve J, Townsend, Jeffrey, Truscott, James, Walker, Martin, Zoueva, Alexandra, NTD Modelling Consortium
Přispěvatelé: Public Health
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Chagas disease
Kala-azar
Psychological intervention
Mycology & Parasitology
Disease
Review
ECONOMIC-EVALUATION
Onchocerciasis
0302 clinical medicine
1108 Medical Microbiology
Medicine
Schistosomiasis
030212 general & internal medicine
Lymphatic filariasis
Neglected tropical diseases
Visceral leishmaniasis
Risk of infection
Soil-transmitted helminths
Neglected Diseases
3. Good health
Infectious Diseases
1117 Public Health And Health Services
Risk analysis (engineering)
Mass drug administration
Life Sciences & Biomedicine
AFRICA
medicine.medical_specialty
CHAGAS-DISEASE
Elimination
WUCHERERIA-BANCROFTI INFECTION
030231 tropical medicine
Biostatistics
Modelling
03 medical and health sciences
SDG 3 - Good Health and Well-being
IVERMECTIN TREATMENT
Leprosy
Disease Transmission
Infectious
Humans
Transmission
Disease Eradication
Trachoma
Science & Technology
business.industry
Public health
Human African trypanosomiasis
Models
Theoretical
medicine.disease
R1
SCHISTOSOMA-HAEMATOBIUM INFECTION
NTD Modelling Consortium
Economic evaluation
Immunology
Communicable Disease Control
Preventive chemotherapy
Parasitology
THERAPEUTIC VACCINE
business
Epidemiologic Methods
ONCHOCERCA-VOLVULUS TRANSMISSION
RC
Zdroj: Parasites & Vectors
Parasites & Vectors, 8. BioMed Central Ltd.
ISSN: 1756-3305
Popis: Quantitative analysis and mathematical models are useful tools in informing strategies to control or eliminate disease. Currently, there is an urgent need to develop these tools to inform policy to achieve the 2020 goals for neglected tropical diseases (NTDs). In this paper we give an overview of a collection of novel model-based analyses which aim to address key questions on the dynamics of transmission and control of nine NTDs: Chagas disease, visceral leishmaniasis, human African trypanosomiasis, leprosy, soil-transmitted helminths, schistosomiasis, lymphatic filariasis, onchocerciasis and trachoma. Several common themes resonate throughout these analyses, including: the importance of epidemiological setting on the success of interventions; targeting groups who are at highest risk of infection or re-infection; and reaching populations who are not accessing interventions and may act as a reservoir for infection,. The results also highlight the challenge of maintaining elimination ‘as a public health problem’ when true elimination is not reached. The models elucidate the factors that may be contributing most to persistence of disease and discuss the requirements for eventually achieving true elimination, if that is possible. Overall this collection presents new analyses to inform current control initiatives. These papers form a base from which further development of the models and more rigorous validation against a variety of datasets can help to give more detailed advice. At the moment, the models’ predictions are being considered as the world prepares for a final push towards control or elimination of neglected tropical diseases by 2020.\ud
Databáze: OpenAIRE
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