Legume vicilins (7S storage globulins) inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells
| Autor: | V. M. Gomes, Tatiana L. Rose, Kátia Valevski Sales Fernandes, Lev A. Okorokov, José Xavier-Filho |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Nystatin
Antifungal Agents Globulin Biophysics Chitin Saccharomyces cerevisiae Biochemistry Vigna Fungal Proteins chemistry.chemical_compound Candida albicans Storage protein Molecular Biology Plant Proteins chemistry.chemical_classification Binding Sites Plants Medicinal biology Cell growth Seed Storage Proteins food and beverages Fabaceae Hydrogen-Ion Concentration Proton Pumps Spores Fungal biology.organism_classification Yeast Spore Culture Media Glucose chemistry Vicilin biology.protein Growth inhibition Carrier Proteins |
| Zdroj: | Biochimica et biophysica acta. 1379(2) |
| ISSN: | 0006-3002 |
| Popis: | Vicilin (7S storage proteins) isolated from different legume seeds were shown to inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells. The degree of growth inhibition varied with the origin of vicilins. It was more than 90% for vicilins from cowpea (Vigna unguiculata, cultivar pitiuba) and equal to 65% for vicilins from Vigna radiata, in the case of Saccharomyces cerevisae. Vicilins from cowpea seeds inhibited the glucose stimulated acidification of the medium by S. cerevisae up to 60%. We have also observed that vicilins bind to yeast cells. We suggest that vicilins bind to chitin-containing structures of yeast cells and that such association could result in inhibition of H+ pumping, cell growth and spore formation. A final consequence of the yeast growth inhibition by vicilins is (probably) the formation of spores. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|