Evaluation of solid pseudopapillary tumor of the pancreas: One tertiary center experience
| Autor: | Mehmet Sait Bugdaci, Hakan Senturk, Iskender Ekinci, Yusuf Kayar, Sebnem Emegil, Ganime Çoban, Nuket Bayram Kayar, Zuhal Gucin, Birol Baysal, Nurcan Unver |
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| Přispěvatelé: | GÜCİN, ZÜHAL |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty One tertiary center experience- Biomedical Research (India) cilt.29 ss.1298-1303 2018 [KAYAR Y. Unver N. ÇOBAN G. GÜCİN Z. EKINCI I. EMEGIL S. KAYAR N. B. BAYSAL B. BUGDACI M. S. ŞENTÜRK H. -Evaluation of solid pseudopapillary tumor of the pancreas] business.industry medicine.drug_class Estrogen receptor medicine.disease Gastroenterology Pathogenesis medicine.anatomical_structure Estrogen Internal medicine Pediatrics Perinatology and Child Health medicine Pancreatic mass Immunohistochemistry Differential diagnosis Pancreas business Pathological |
| Popis: | Solid Pseudo-Papillary Neoplasia (SPN) is the rare tumors of the pancreas. The aim of the current study is documentation of the data of the patients. The data of patients with pancreatic neoplasm were presented to Gastroenterology Department between 2010 and 2014 were evaluated retrospectively. A database of the characteristics of these patients was developed, including demographic, laboratory, radiological, surgical and pathological features and the immuno-histochemical staining of tumor specimens. Analysis of 323 patients diagnosed with pancreas malignancies in our hospital between 2010 and 2014 demonstrated that 5 patients (1.5%) were diagnosed with SPN. Of these five patients, four were females and one was male. Their average age was 27 (range: 16-50). CA 19-9 levels were normal in four patients while slightly increase in one (60 U/mL (0-33)) and there were the other tumor markers under a normal range 5-10.3 cm diameter in size, mean: 7.6 cm. Immunohistochemical analysis demonstrated that CD10, CD56, Ki-67 and β-catenine was positive for all patients while other markers were variable. Progesteron and estrogen receptors were positive in histo-pathologic specimens of four patients. SPN is a rare tumor that develops principally in young women and has a good prognosis. Immunohistochemical staining is important in the differential diagnosis of SPN and estrogen positivity may have a role in pathogenesis of a limited patients. |
| Databáze: | OpenAIRE |
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