Prunus spinosa L. leaf extracts: polyphenol profile and bioactivities
| Autor: | Željko Žižak, Ivona Veličković, Slavica Grujic, Marija Ivanov, Nemanja Rajčević, Marina Soković, Petar D. Marin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
DPPH Agriculture (General) Flavonoid antioxidant activity Plant Science Horticulture 01 natural sciences S1-972 chemistry.chemical_compound 0404 agricultural biotechnology Acetone leaf extracts Prunus spinosa antitumor activity Phenols Food science enzyme-inhibitory activity anthocyanins chemistry.chemical_classification ABTS biology food and beverages Forestry 04 agricultural and veterinary sciences SD1-669.5 biology.organism_classification 040401 food science chemistry Polyphenol Anthocyanin Agronomy and Crop Science 010606 plant biology & botany |
| Zdroj: | Notulae Botanicae Horti Agrobotanici Cluj-Napoca, Vol 49, Iss 1 (2021) |
| ISSN: | 1842-4309 |
| Popis: | Prunus spinosaleaf extracts in solvents of different polarity (water, ethanol and acetone), their phenol,flavonoid and anthocyanin contents and biological properties were the object of this study. The richest in phenols as well as in flavonoids was acetone extract with 181.19 mg GAE and 80.10 mg QE per gram of dry extract, respectively. Moreover, the quantity of anthocyanins obtained byHPLC analysis was also the highestin acetone sample. Examined samples possessed antioxidant properties evaluated through fourin vitroassays(DPPH, ABTS, FRAP and TRC). The acetone extract wasproved to be the best antioxidant among testedsamples, which could be ascribed to polyphenols, especially anthocyanins. The aqueous and the ethanolextractexhibited antibacterial effects, being particularlyactive againstB. cereusandE. cloacaeT. viride P.funiculosum,P. ochrochloronP. verrucosumvar.cyclopiumwere the most susceptible among fungalmicroorganisms examined. Both, the aqueous and theethanol extract expressed inhibitory activity towardsenzymes linked to diabetes mellitus type II. Additionally, the ethanol extract showedsignificantly higherpotential in inhibitingα-glucosidase than the drug used as the positive control. Furthermore, the aqueoussample revealed antitumor effects on following malignant cell lines: HeLa, K562 and MDA-MB-453. Theresults presented herein suggest thatP. spinosaleaves should be considered as a natural source ofbioactivecompounds with potential application in phytopharmacy and food industry. |
| Databáze: | OpenAIRE |
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