Additive effects of lactation and food restriction to increase hypothalamic neuropeptide Y mRNA in rats
| Autor: | M.O. Ajala, P.D. Lambert, John P.H. Wilding, S.R. Bloom |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment media_common.quotation_subject Hypothalamus Biology Eating Endocrinology Pregnancy Internal medicine Lactation medicine Animals Insulin Neuropeptide Y RNA Messenger Rats Wistar Pancreatic hormone media_common Appetite Luteinizing Hormone medicine.disease Neuropeptide Y receptor Rats medicine.anatomical_structure Female Food Deprivation Luteinizing hormone |
| Zdroj: | Journal of Endocrinology. 152:365-369 |
| ISSN: | 1479-6805 0022-0795 |
| DOI: | 10.1677/joe.0.1520365 |
| Popis: | Neuropeptide Y (NPY) is the most powerful appetite stimulant known, and rates of synthesis and release in the hypothalamus correlate closely with nutritional status. Pregnancy and lactation provide an excellent model of physiological hyperphagia. In this study the authors measured food intake, plasma glucose, insulin and luteinizing hormone (LH) and hypothalamic NPY mRNA in rats during pregnancy and in early and late lactation. The effect of food restriction (to 80% of control) during lactation was also studied. Pregnancy resulted in a modest increase in daily food intake over non-lactating controls (controls: 15·6±0·6 g, pregnant: 19·8±1·1 g, PPPPP Journal of Endocrinology (1997) 152, 365–369 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|