Medically attended pediatric influenza during the resurgence of the Victoria lineage of influenza B virus
| Autor: | W. Paul Glezen, Gail J. Demmler, Flor M. Munoz, Ladonna K. Hite |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Microbiology (medical) Pediatrics medicine.medical_specialty Adolescent Influenza vaccine Orthomyxoviridae medicine.disease_cause 03 medical and health sciences Influenza complications 0302 clinical medicine 030225 pediatrics Influenza Human Influenza A virus medicine Humans 030212 general & internal medicine Child Respiratory Tract Infections Retrospective Studies Myositis biology Respiratory tract infections business.industry Influenzavirus B Incidence (epidemiology) Infant Newborn Infant virus diseases General Medicine Vaccine efficacy biology.organism_classification Texas Influenza 3. Good health Hospitalization Influenza B virus Infectious Diseases Child Preschool Immunology Human mortality from H5N1 Female Immunization business |
| Zdroj: | International Journal of Infectious Diseases. 11:40-47 |
| ISSN: | 1201-9712 |
| DOI: | 10.1016/j.ijid.2005.10.008 |
| Popis: | Summary Objectives During the 2002–2003 season, a new variant of influenza B co-circulated with influenza A viruses. This study examines the characteristics and outcomes of children with influenza A and B virus infection vs. other acute respiratory illnesses. Methods A retrospective chart review was performed on children with laboratory-confirmed influenza infection, and influenza negative acute respiratory illnesses that prompted a hospital visit. Results Children with influenza were more often previously healthy and presenting with upper respiratory symptoms, while influenza negative patients typically had underlying medical conditions, and lower respiratory tract disease. Children with influenza B were older, were more likely to be in school, and presented with myositis more frequently than those with influenza A. A third of children with influenza A, and 42% with influenza B required hospitalization. The highest hospitalization rates were in infants under one year. No healthy children, and only 15% of those with chronic medical problems, had received influenza vaccine. Vaccine efficacy was estimated to be 82.6%. Conclusions Most children with influenza were previously healthy. Overall, a third of children with influenza required hospitalization. Influenza A and B were clinically indistinguishable, except for older age and higher incidence of myositis in patients with influenza B. Influenza vaccine coverage in both healthy and high-risk children was low. |
| Databáze: | OpenAIRE |
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