A method for determination of blood flow with 133Xe in human nasal mucosa
| Autor: | Knut Flisberg, Per Ohlin, Ingemar Larsson, Peter Olsson, Mats Bende |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Radioisotope Dilution Technique Oxymetazoline Disappearance rate Mucous membrane of nose Laryngectomy General Medicine Blood flow Middle Aged chemistry.chemical_compound Nasal Mucosa Otorhinolaryngology chemistry Regional Blood Flow Vasoactive medicine Humans Radioisotope dilution technique Histamine Xenon Radioisotopes medicine.drug Aged |
| Zdroj: | Acta oto-laryngologica. 96(3-4) |
| ISSN: | 0001-6489 |
| Popis: | The 133Xe wash-out technique was used as a method for calculation of the blood flow in human nasal mucosa. The disappearance of 133Xe from the nasal mucosa was followed using scintillation detectors. In laryngectomies it was shown that the disappearance of 133Xe from the mucosa depended mainly on the blood flow. Leakage of 133Xe from the mucosa to the nasal air was unimportant. The disappearance rate of 133Xe was decreased by oxymetazoline and increased by histamine, mostly likely due to the effects of these vasoactive drugs on the mucosa blood flow. The 133Xe wash-out technique would seem to be a simple method to study nasal mucosal blood-flow changes in humans. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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