Impact of biliary complications on quality of life in live-donor liver transplant recipients
| Autor: | Mahmoud El-Meteini, Mohamed Bahaa, Ghada Abdelrahman Mohamed, Hany Dabbous, M. Salah, Reginia Nabil Guirguis, Wesam A. Ibrahim, Iman F. Montasser, Ehab H. Nashaat, Azza Emam Yassin, Mohamed Fathy, Shereen A. Saleh |
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| Rok vydání: | 2021 |
| Předmět: |
Quality of life
medicine.medical_specialty Cirrhosis Hepatology Live donor business.industry Live-donor liver transplantation medicine.disease Mental health Biliary complications surgical procedures operative Quality of life (healthcare) medicine Retrospective Cohort Study The Short Form 12 version 2 Intensive care medicine business |
| Zdroj: | World Journal of Hepatology |
| ISSN: | 1948-5182 |
| DOI: | 10.4254/wjh.v13.i10.1405 |
| Popis: | BACKGROUND Despite significant advancements in liver transplantation (LT) surgical procedures and perioperative care, post-LT biliary complications (BCs) remain a significant source of morbidity, mortality, and graft failure. In addition, data are conflicting regarding the health-related quality of life (HRQoL) of LT recipients. Thus, the success of LT should be considered in terms of both the survival and recovery of HRQoL. AIM To assess the impact of BCs on the HRQoL of live-donor LT recipients (LDLT-Rs). METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our institution. The Short Form 12 version 2 (SF 12v2) health survey was used to assess their HRQoL. We also included 25 LDLT-Rs without any post-LT complications as a control group. RESULTS The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning (P = 0.003), role-physical (P < 0.001), bodily pain (P = 0.003), general health (P = 0.004), social functioning (P = 0.005), role-emotional (P < 0.001), and mental health (P < 0.001). No significant difference between the two groups regarding vitality was detected (P = 1.000). The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains (P < 0.001) and the mental (P < 0.001) and physical (P = 0.0002) component summary scores. CONCLUSION The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL. |
| Databáze: | OpenAIRE |
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