Toxoplasma Gondii Infection and Depression: A Case—Control Seroprevalence Study
| Autor: | Jesús Hernández-Tinoco, Elizabeth Rábago-Sánchez, Luis Francisco Sánchez-Anguiano, Gabriel Molotla-de-León, Luis Omar Berumen-Segovia, Oliver Liesenfeld, Sergio Estrada-Martínez, Isabel Beristain-Garcia, Cosme Alvarado-Esquivel, María Nalleli Ortiz-Jurado, Alma Rosa Pérez-Álamos, Yazmin Elizabeth Torres-Prieto |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Population
lcsh:QR1-502 Toxoplasma gondii Toxoplasmagondii lcsh:Microbiology 03 medical and health sciences 0302 clinical medicine parasitic diseases Seroprevalence Psychiatric hospital Medicine education Depression (differential diagnoses) education.field_of_study biology seroprevalence business.industry psychiatric patients Case-control study case–control study Control subjects biology.organism_classification 030227 psychiatry Immunology depression biology.protein Original Article Antibody business 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Microbiology & Immunology, Vol 6, Iss 2, Pp 085-089 (2016) European Journal of Microbiology & Immunology |
| ISSN: | 2062-8633 |
| Popis: | We assessed the association of Toxoplasma gondii infection and depression in a sample of psychiatric patients and control subjects without depression. We performed an age- and gender-matched case-control study of 89 patients suffering from depression attended in a public psychiatric hospital in Durango City, Mexico and 356 control subjects without depression from the general population of the same city. Participants were tested for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays. Anti-T. gondii IgG antibodies were found in 11 (12.4%) of the 89 cases and in 22 (6.2%) of the 356 controls (OR = 2.14; 95% CI: 1.00-4.59; P = 0.04). Anti-T. gondii IgM antibodies were found in four (19%) of 21 anti-T. gondii IgG seropositive controls but not in 11 anti-T. gondii IgG seropositive cases (P = 0.27). Patients aged 30 years old and younger had a significantly higher seroprevalence of T. gondii infection than controls of the same age group (P = 0.001). Results of the present study suggest a potential association between T. gondii infection and depression. Furthers studies to confirm our results and to determine the epidemiology of T. gondii in young depressed patients should be conducted. |
| Databáze: | OpenAIRE |
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