The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations
| Autor: | Paul S. Tofts, Anwar R. Padhani, D McIntyre, R. J. Maxwell, Patricia M Price, Gordon C Jayson, Gordon J. S. Rustin, John C. Waterton, Ian Judson, Paul Workman, Martin O. Leach, John R. Griffiths, Michael R. Horsman, R Rathbone, Kevin M. Brindle, Alan Jackson, Jeffrey L. Evelhoch, Stephen R. Williams, W Vennart, Michael V. Knopp, Gillian M. Tozer |
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| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
antivascular
Cancer Research Bone marrow transplant medicine.medical_specialty BRAIN-TUMORS Cancer therapy Angiogenesis Inhibitors Antineoplastic Agents GADOPENTETATE DIMEGLUMINE ANGIOGENESIS BREAST-TUMORS magnetic resonance CONTRAST-ENHANCED MRI Neoplasms Terminology as Topic END-POINTS Clinical Studies medicine therapeutic trials 1112 Oncology and Carcinogenesis Medical physics Oncology & Carcinogenesis Stage (cooking) Clinical Trials as Topic Science & Technology medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging antiangiogenic QUANTITATIVE-ANALYSIS equipment and supplies CANCER Therapeutic trial Magnetic Resonance Imaging Biomarker (cell) Surgery Clinical trial CEREBRAL BLOOD-VOLUME Pharmacodynamic/Pharmacokinetic Technologies Advisory Committee Drug Development Office Cancer Research UK Oncology Evaluation Studies as Topic ENDOTHELIAL GROWTH-FACTOR Anti cancer drugs biomarker cancer therapy business Life Sciences & Biomedicine human activities |
| Zdroj: | British Journal of Cancer Leach, M O, Brindle, K M, Evelhoch, J L, Griffiths, J R, Horsman, M R, Jackson, A, Jayson, C G, Judson, I R, Knopp, M V, Maxwell, R J, McIntyre, D, Padhani, A R, Price, P, Rathbone, R, Rustin, G J, Tofts, P S, Tozer, G M, Vennart, W, Waterton, J C, Williams, S R & Workman, P 2005, ' The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations ', Br. J. Cancer, vol. 92, no. 9, pp. 1599-1610 . https://doi.org/10.1038/sj.bjc.6602550 94th Annual Meeting of the American-Association-for-Cancer-Research |
| ISSN: | 1532-1827 0007-0920 |
| Popis: | Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.\ud \ud \ud |
| Databáze: | OpenAIRE |
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