Why should primary care physicians know about breast cancer genetics?
Autor: | Julie Bars Culver, Ephrat Levy-Lahad, Mary B. Daly, Judith Hull, Linda E. Pinsky, Wylie Burke |
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Rok vydání: | 2001 |
Předmět: |
Adult
Breast biopsy medicine.medical_specialty medicine.medical_treatment Genes BRCA1 Breast Neoplasms Risk Assessment Article Breast cancer Health care Prevalence medicine Humans Genetic Predisposition to Disease Genetic Testing Family history Ovarian Neoplasms Gynecology Primary Health Care medicine.diagnostic_test business.industry Hormone replacement therapy (menopause) General Medicine medicine.disease United States Family medicine Menarche Female Clinical Competence Breast Cancer Genetics business Live birth |
Zdroj: | Western Journal of Medicine. 175:168-173 |
ISSN: | 0093-0415 |
Popis: | Funding: The development of this material was supported in part through funding from the Genetics in Primary Care (GPC): A Faculty Development Initiative. The GPC is a contract (# 240-98-0020) funded by the Maternal and Child Health Bureau and Bureau of Health Professions, Health Resources and Services Administration, with co-funding from the National Human Genome Research Institute, National Institutes of Health, and the Agency for Healthcare Research and Quality. Your patient, a 36-year-old woman, recently learned that her former college roommate was diagnosed with breast cancer. She wants to know if she should have the genetic test her friend mentioned to assess her risk. Her only family history is that her mother has breast cancer at age 72. She mentions that her roommate did not have a family history of breast cancer, “except on her father's side, and that doesn't count.” Table 1 Nongenetic contributors to breast cancer risk Menarche before age 12 years Menopause after age 55 years First live birth after age 30 years Nulliparity Previous breast biopsies Atypical hyperplasia diagnosed by breast biopsy Obesity Alcohol use Hormone replacement therapy Excessive radiation exposure View it in a separate window |
Databáze: | OpenAIRE |
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