| Autor: |
Thomas Hoffmann, Marco Kalmar, Fabian Klink, Jörg Sauerhering |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Current Directions in Biomedical Engineering, Vol 5, Iss 1, Pp 537-540 (2019) |
| ISSN: |
2364-5504 |
| DOI: |
10.1515/cdbme-2019-0135 |
| Popis: |
Phantoms mimicking special physiological processes of the human body are essential for evaluating prototypes of medical devices. Especially for thermometric MRI measurements, the temperature distribution in the brain needs to be simulated. Since this parameter is dependent on the tissue perfusion, a new hydrogel by MAGDASSIS et al. was evaluated in this work for building models with hollow artery structures. This hydrogel can be polymerized through UV-light due to the nanoparticles contained in it. Additionally, thermal parameters were measured and compared to human brain tissue. The indirect manufacturing of hydrogel phantoms showed good qualitative results for vessels with a diameter > 3 mm. In this process a 3D printed wax core was inserted in the hydrogel and the structure was then UV cured after molding. After curing the core was dissolved in an isopropanol bath. The thermal properties, obtained by the transient planesource- method, showed similar values compared to that of human brain tissue mentioned in literature. Further limitations in the manufacturing process needs to be overcome to use the indirect manufacture approach for smaller vessels of the brain. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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