Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View

Autor: Katherine J. Taylor, Cecilie D. Amdal, Kristin Bjordal, Guro L. Astrup, Bente B. Herlofson, Fréderic Duprez, Ricardo R. Gama, Alexandre Jacinto, Eva Hammerlid, Melissa Scricciolo, Femke Jansen, Irma M. Verdonck-de Leeuw, Giuseppe Fanetti, Orlando Guntinas-Lichius, Johanna Inhestern, Tatiana Dragan, Alexander Fabian, Andreas Boehm, Ulrike Wöhner, Naomi Kiyota, Maximilian Krüger, Pierluigi Bonomo, Monica Pinto, Sandra Nuyts, Joaquim C. Silva, Carmen Stromberger, Francesco Tramacere, Ayman Bushnak, Pietro Perotti, Michaela Plath, Alberto Paderno, Noa Stempler, Maria Kouri, Susanne Singer
Přispěvatelé: Otolaryngology / Head & Neck Surgery, APH - Mental Health, CCA - Cancer Treatment and quality of life, APH - Personalized Medicine
Rok vydání: 2023
Předmět:
Zdroj: Taylor, K J, Amdal, C D, Bjordal, K, Astrup, G L, Herlofson, B B, Duprez, F, Gama, R R, Jacinto, A, Hammerlid, E, Scricciolo, M, Jansen, F, Verdonck-de Leeuw, I M, Fanetti, G, Guntinas-Lichius, O, Inhestern, J, Dragan, T, Fabian, A, Boehm, A, Wöhner, U, Kiyota, N, Krüger, M, Bonomo, P, Pinto, M, Nuyts, S, Silva, J C, Stromberger, C, Tramacere, F, Bushnak, A, Perotti, P, Plath, M, Paderno, A, Stempler, N, Kouri, M & Singer, S 2023, ' Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View ', Healthcare (Switzerland), vol. 11, no. 6, 906 . https://doi.org/10.3390/healthcare11060906
Healthcare (Switzerland), 11(6):906. MDPI AG
Healthcare; Volume 11; Issue 6; Pages: 906
ISSN: 2227-9032
DOI: 10.3390/healthcare11060906
Popis: The long-term problems of head and neck cancer survivors (HNCS) are not well known. In a cross-sectional international study aimed at exploring the long-term quality of life in this population, 1114 HNCS were asked to state their two most serious long-term effects. A clinician recorded the responses during face-to-face appointments. A list of 15 example problems was provided, but a free text field was also available. A total of 1033 survivors responded to the question. The most frequent problems were ‘dry mouth’ (DM) (n = 476; 46%), ‘difficulty swallowing/eating’ (DSE) (n = 408; 40%), ‘hoarseness/difficulty speaking’ (HDS) (n = 169; 16%), and ‘pain in the head and neck’ (PHN) (n = 142; 14%). A total of 5% reported no problems. Logistic regression adjusted for age, gender, treatment, and tumor stage and site showed increased odds of reporting DM and DSE for chemo-radiotherapy (CRT) alone compared to surgery alone (odds ratio (OR): 4.7, 95% confidence interval (CI): 2.5–9.0; OR: 2.1, CI: 1.1–3.9), but decreased odds for HDS and PHN (OR: 0.3, CI: 0.1–0.6; OR: 0.2, CI: 0.1–0.5). Survivors with UICC stage IV at diagnosis compared to stage I had increased odds of reporting HDS (OR: 1.9, CI: 1.2–3.0). Laryngeal cancer survivors had reduced odds compared to oropharynx cancer survivors of reporting DM (OR: 0.4, CI: 0.3–0.6) but increased odds of HDS (OR: 7.2, CI: 4.3–12.3). This study provides evidence of the serious long-term problems among HNCS.
Databáze: OpenAIRE
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