Comparative Analysis of Antioxidant Properties of Comenic Acid and Potassium Comenate in Modeled Immobilization Stress
| Autor: | N. O. Abramova, L. V. Shurygina, L. I. Zlishcheva, A. N. Kravtsova, V. V. Khablyuk, A. A. Kravtsov, E. I. Zlishcheva |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Restraint Physical Antioxidant medicine.medical_treatment Carboxylic Acids Oxidative phosphorylation Pharmacology medicine.disease_cause Antioxidants General Biochemistry Genetics and Molecular Biology Comenic acid Stress (mechanics) Mice chemistry.chemical_compound Malondialdehyde Animals Outbred Strains medicine Animals General Medicine Oxidative Stress Biochemistry chemistry Pyrones Potassium comenate Free radical oxidation Stress Psychological Oxidative stress |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 159:466-468 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | We studied antioxidant protective effect of comenic acid and potassium comenate in doses of 2, 4, and 8 mg/kg under conditions of oxidative stress in the brain of mice exposed to immobilization stress. Administration of potassium comenate and comenic acid in the above doses for 3 days before stress prevented the development of oxidative processes in the brain of stressed animals. The antioxidant effect of potassium comenate more pronounced. |
| Databáze: | OpenAIRE |
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