Long-Term Body Composition Changes in Women Following Roux-en-Y Gastric Bypass Surgery
Autor: | Jennifer R. Mager, Carrie P. Earthman, Shalamar D. Sibley, Abigail J. Cole, Adam J. Kuchnia, Lauren M. Beckman, Cyrus Jahansouz |
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Rok vydání: | 2016 |
Předmět: |
Adult
Blood Glucose 0301 basic medicine medicine.medical_specialty Gastric Bypass Medicine (miscellaneous) 030209 endocrinology & metabolism medicine.disease_cause Article Body Mass Index 03 medical and health sciences Absorptiometry Photon 0302 clinical medicine Japan Weight loss Hand strength Weight Loss medicine Humans Longitudinal Studies Dual-energy X-ray absorptiometry Aged 030109 nutrition & dietetics Nutrition and Dietetics Hand Strength medicine.diagnostic_test Gastric bypass surgery business.industry nutritional and metabolic diseases Middle Aged Roux-en-Y anastomosis Obesity Morbid Surgery Cohort Body Composition Lean body mass Female medicine.symptom Energy Metabolism business Body mass index Follow-Up Studies |
Zdroj: | Journal of Parenteral and Enteral Nutrition. 41:583-591 |
ISSN: | 1941-2444 0148-6071 |
DOI: | 10.1177/0148607115625621 |
Popis: | Although most individuals experience successful weight loss following Roux-en-Y gastric bypass (RYGB), weight regain is a concern, the composition of which is not well documented. Our aim was to evaluate changes in body composition and handgrip strength as a measure of functional status in participants from a previous 1-year post-RYGB longitudinal study who had undergone RYGB approximately 9 years prior.Five women from an original larger cohort were monitored pre-RYGB and 1.5 months, 6 months, 1 year, and 9 years post-RYGB. Body composition was assessed at all time points using dual energy x-ray absorptiometry and multiple dilution. Handgrip strength was measured using a digital isokinetic hand dynamometer (Takei Scientific Instruments, Ltd, Tokyo, Japan).Mean time to final follow-up was 8.7 years. Lean soft tissue (LST) loss over the ~9-year period was on average 11.9 ± 5.6 kg. Compared with 1-year post-RYGB, 9-year LST was 4.4 ± 3.0 kg lower ( P = .03). Fat-free mass decreased over the 9-year period by 12.6 ± 5.8 kg. Mean fat mass (FM) decreased from 75.4 ± 22.6 kg pre-RYGB to 35.5 ± 21.5 kg 1 year post-RYGB but then trended toward an increase of 8.6 ± 7.0 kg between 1 year and 9 years post-RYGB ( P = .053). Loss of LST was correlated with loss of handgrip strength ( r = 0.64, P = .0005).The continued loss of lean mass associated with decreased handgrip strength occurring with long-term trend toward FM regain post-RYGB is concerning. The loss of LST and functional strength carries particular implications for the aging bariatric population and should be investigated further. |
Databáze: | OpenAIRE |
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