Peri-device leakage not CHA2DS2-VASc is associated with post-left atrial appendage closure cardiovascular event

Autor:	Pang-Shuo Huang, Fu-Chun Chiu, Hsiao-Liang Cheng, Jung-Cheng Hsu, Su-Kiat Chua, Chun-Yuan Chu, Ting-Tse Lin, Jien-Jiun Chen, Chia-Ti Tsai
Rok vydání:	2022
Předmět:	Aged 80 and over Rehabilitation Thrombosis Middle Aged Stroke Treatment Outcome Ischemic Attack Transient Atrial Fibrillation Humans Surgery Atrial Appendage Neurology (clinical) Cardiology and Cardiovascular Medicine Aged Follow-Up Studies Ischemic Stroke
Zdroj:	Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 31(11)
ISSN:	1532-8511
Popis:	In patients with non-valvular atrial fibrillation (NVAF), the left atrial appendage occluder (LAAO) is an alternative treatment for stroke prevention. However, thromboembolic event still occur, and the predictors are unknown.The first Asian long-term follow-up study consisted of 308 patients with mean age 71.9±9.5 years, mean CHAThere was no procedural-related TIA or stroke. After a mean follow-up of 38±16 months, the ischemic stroke/TIA rate was 1.9 and cardiovascular death rate 0.3 per 100 patient-year. The rate of peri-device leak (PDL) was 11.9% and device-related thrombus (DRT) 2.6%. In the multivariable analyses, PDL was the only independent predictor of stroke/TIA (hazard ratio 5.5, p=0.008). CHAPDL is the only independent predictor of post-LAAO stroke. The risk of stroke for patients with NVAF may be controllable after LAA is occluded, because PDL is preventable and treatable.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb5f5052c68c99638f34809e002776f https://pubmed.ncbi.nlm.nih.gov/36095860 Zobrazit plný text záznamu Full Text from ScienceDirect