Functional remediation for patients with bipolar II disorder: improvement of functioning and subsyndromal symptoms
| Autor: | Francesc Colom, PATRICIA VEGA PEREZ, Gonzalo Daniel Galván, María Mayoral, Ramón Landin-Romero, ANGELA IBAÑEZ, Marta Rapado-Castro, Virginia Soria, Patricia Correa Ghisays, Vicent Balanzá-Martínez, Ana María González-Pinto, Barbara Segura, Jose Menchon, Sara Soria Pastor, Inmaculada Fuentes Durá, ESTHER JIMENEZ, Benedikt L Amann, Pilar A. Saiz, Rafael Tabares-Seisdedos, Jose Luis Ayuso-Mateos, Anabel Martinez-Aran, Adriane Rosa, Caterina del Mar Bonnín, Susana Al-Halabí, JESSICA MERCHÁN NARANJO, Paz Garcia-Portilla, Jose Sanchez-Moreno, Julio Bobes, Brisa Solé, Analucia Alegria, Eduard Vieta, Sara Barbeito Resa, Silvia Alonso-Lana |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Bipolar Disorder medicine.medical_treatment law.invention Bipolar II disorder Cognition Randomized controlled trial law Internal medicine Psychoeducation medicine Humans Pharmacology (medical) Single-Blind Method Bipolar disorder Biological Psychiatry Pharmacology Psychiatric Status Rating Scales Cognitive Behavioral Therapy medicine.disease Cognitive behavioral therapy Psychiatry and Mental health Treatment Outcome Neurology Cognitive remediation therapy Female Neurology (clinical) medicine.symptom Psychology Neurocognitive Mania Clinical psychology |
| Zdroj: | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 25(2) |
| ISSN: | 1873-7862 |
| Popis: | Recently, Functional Remediation (FR) has proven to be effective in improving the functional outcome of euthymic bipolar patients. The aim of this study was to test the efficacy of the FR program in a subsample of euthymic bipolar II patients (BPII). A post-hoc analyses were undertaken using data of 53 BPII outpatients who had participated in a multicenter, rater-blind, randomized, controlled trial exploring the efficacy of FR (n=17) as compared with a Psychoeducation group (PSY) (n=19) and a treatment as usual control group (TAU n=17). The primary outcome variable was the functional improvement defined as the mean change in the Functioning Assessment Short Test (FAST) from baseline to endpoint after the intervention. Regarding the treatment effect, data reveal a significant functional improvement from baseline to endpoint, suggestive for an interaction between program pertinence and time (pre-post). Nevertheless, Tukey׳s post-hoc test only revealed a trend in favor of a better outcome for FR when compared to the other two groups. We also found an interaction between program pertinence and time when analysing the subdepressive symptoms, with BPII patients in FR showing a significant reduction when compared to the PSY group. Our results suggest that the FR appears to be effective in improving the overall functional outcome in BPII, as well as in reducing subdepressive symptoms. |
| Databáze: | OpenAIRE |
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