Postmortem evidence of disseminated Zika virus infection in an adult patient

Autor: Ravindran Thayan, Giri Shan Rajahram, Gillian Hale, Kum Thong Wong, Julu Bhatnagar, Tsin W. Yeo, Timothy William, Jessie Hiu, Paul A. Tambyah
Přispěvatelé: Lee Kong Chian School of Medicine (LKCMedicine)
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Infectious Diseases. 83:163-166
ISSN: 1201-9712
Popis: Fatal complications associated with the Zika virus (ZIKV) have rarely been reported in adults, and detailed postmortem reports are limited (Musso and Gubler, 2016). ZIKV infection is typically a mild uncomplicated febrile illness associated with arthralgia, rash, and conjunctivitis (Duffy et al., 2009). In adults, fatal and non-fatal neurological complications have been reported, including encephalitis and Guillain–Barré syndrome (Soares et al., 2016, Oehler et al., 2014). Non-neurological fatalities have also been reported sporadically in patients from Latin America, who have presented with an acute febrile illness and multi-organ failure (Sarmiento-Ospina et al., 2016, Zonneveld et al., 2016). This report describes the clinical features and postmortem findings of a 61-year-old Malaysian male with co-morbidities, who had a fatal outcome subsequent to an acute febrile and rash illness, with pre- and postmortem evidence of ZIKV infection. Published version
Databáze: OpenAIRE