A D-optimal design to model the performances of dressings and devices for negative pressure wound therapy
Autor: | Carl Saxby, R. Smajda, F. Di Francesco, Pietro Salvo, Marco Romanelli, Valentina Dini, Guy Voirin |
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Rok vydání: | 2016 |
Předmět: |
Exudate
Optimal design medicine.medical_specialty medicine.medical_treatment Transit time Dermatology Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Negative-pressure wound therapy medicine Chronic wounds D-optimal design Exudate transit time Negative pressure wound therapy Wound dressing D-optimal design Chronic wounds integumentary system business.industry Wound.exudate 030208 emergency & critical care medicine Exudates and Transudates Negative pressure wound therapy Models Theoretical Bandages Surgery Model parameter Wound dressing Exudate transit time medicine.symptom business Negative-Pressure Wound Therapy Biomedical engineering |
Zdroj: | Journal of Tissue Viability. 25:83-90 |
ISSN: | 0965-206X |
DOI: | 10.1016/j.jtv.2016.01.001 |
Popis: | A D-optimal design was used to identify and model variables that affect the transit time of wound exudate through an illustrative dressing used for negative pressure wound therapy. Many authors have addressed the clinical benefits of negative pressure wound therapy, but limited information is available on how to assess performances of dressings. In this paper, the transit time of wound exudate through a dressing was chosen as a model parameter to show how experimental design (DOE) can be used for this purpose. Results demonstrated that rate of exudate production, temperature and dressing thickness were the variables with the largest impact on transit time. The DOE approach could be used to model other dressing properties, like for example capability of absorbing excess exudate or breathability. |
Databáze: | OpenAIRE |
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