Asymptomatic carotid stenosis and concomitant silent brain infarctions
| Autor: | Claudina Rudolph, Nikolaj Eldrup |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Brain Infarction
medicine.medical_specialty medicine.medical_treatment 030204 cardiovascular system & hematology silent brain infarct Asymptomatic Risk Assessment 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Prevalence Dementia Humans Radiology Nuclear Medicine and imaging Carotid Stenosis Endarterectomy Asymptomatic Diseases Endarterectomy Carotid Asymptomatic carotid stenosis medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine medicine.disease Prognosis Magnetic Resonance Imaging Stenosis Brain infarction Concomitant Cardiology Surgery medicine.symptom Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery dementia |
| Zdroj: | Rudolph, C & Eldrup, N 2020, ' Asymptomatic carotid stenosis and concomitant silent brain infarctions ', Vascular, vol. 28, no. 1, pp. 7-15 . https://doi.org/10.1177/1708538119858258 |
| DOI: | 10.1177/1708538119858258 |
| Popis: | Objectives This review aims to clarify (1) the definition of silent brain infarct (SBI), (2) the diagnostic criteria of SBI using magnetic resonance imaging (MRI), (3) the prevalence of patients with asymptomatic carotid stenosis and SBI based on MRI assessment, (4) the association of SBI and asymptomatic carotid stenosis and the risk of stroke compared to patients without SBI, (5) the association between development of dementia/cognitive impairment in people with asymptomatic carotid stenosis and SBI, and (6) the evidence for treating patients with carotid stenosis and SBI. Methods A systematic search of PubMed and Scopus including all studies published from 2000 to 2018 and written in English. Results No consensus of the definition and diagnostic criteria for SBI was found. The prevalence of SBI in asymptomatic carotid patients is 17–33.3%. SBI is a significant risk factor for future stroke, OR 4.6 (95% CI: 3.0–7.2; p Conclusion This review emphasizes the need to standardize the definition and diagnostic criteria of SBI on MRI. Current evidence suggests an increased risk and a small potential benefit of offering carotid endarterectomy to patient with silent brain infarct. Prospective studies are warranted to elucidate these issues further. |
| Databáze: | OpenAIRE |
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