Cadherins and their connections: adhesion junctions have broader functions

Autor: Patrick M. McNutt, Malcolm S. Steinberg
Rok vydání: 1999
Předmět:
Zdroj: Current Opinion in Cell Biology. 11:554-560
ISSN: 0955-0674
DOI: 10.1016/s0955-0674(99)00027-7
Popis: Cadherins — a family of cell–cell adhesion molecules — are linked to the actin cytoskeleton via intervening proteins. Recent results address molecular explanations for observed cadherin behavior, point to signals that regulate adhesion by modulating elements of the cadherin-associated complex, challenge the belief that different cadherins generally cannot cross-adhere, and highlight instructive roles for cadherins in cell signaling and differentiation.
Databáze: OpenAIRE