Cadherins and their connections: adhesion junctions have broader functions
Autor: | Patrick M. McNutt, Malcolm S. Steinberg |
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Rok vydání: | 1999 |
Předmět: |
Delta Catenin
Macromolecular Substances Biology Models Biological Structure-Activity Relationship Cell–cell interaction Nectin Cell Adhesion Animals Humans Phosphorylation Cell adhesion Cytoskeleton beta Catenin Binding Sites Cadherin Cell adhesion molecule Catenins Cell Differentiation Cell Biology Adhesion Cadherins Phosphoproteins Actin cytoskeleton Actins Protein Structure Tertiary Cell biology Cytoskeletal Proteins Intercellular Junctions Desmoplakins Catenin Trans-Activators Cell Adhesion Molecules Protein Processing Post-Translational Protein Binding |
Zdroj: | Current Opinion in Cell Biology. 11:554-560 |
ISSN: | 0955-0674 |
DOI: | 10.1016/s0955-0674(99)00027-7 |
Popis: | Cadherins — a family of cell–cell adhesion molecules — are linked to the actin cytoskeleton via intervening proteins. Recent results address molecular explanations for observed cadherin behavior, point to signals that regulate adhesion by modulating elements of the cadherin-associated complex, challenge the belief that different cadherins generally cannot cross-adhere, and highlight instructive roles for cadherins in cell signaling and differentiation. |
Databáze: | OpenAIRE |
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