Gonococci resistant to current antimicrobial management standards: a new threat to global public health

Autor: Tauanne F dos Santos, Mellânia R Goveia, Gleyson MA Moraes, Marco ASB Tavares, Silvio RA Davalos, Camila BS Campos, Fernando A de Oliveira, Diego FD Benitez, Maria B Tavares, Emillene de H Colli, Maria EL Pinheiro, Barbara dos RDL Rodrigues, Celso DLR Neto, Rafaela S Ribeiro
Rok vydání: 2022
Předmět:
Zdroj: Future Microbiology. 17:1241-1247
ISSN: 1746-0921
1746-0913
DOI: 10.2217/fmb-2022-0110
Popis: Gonorrhea is the second most common sexually transmitted bacterial infection on the planet and is caused by a Gram-negative cocco, Neisseria gonorrhoeae. Currently, the preferred regimen for the management of this disease in Brazil is a combination of antimicrobials, in this case, ceftriaxone and azithromycin. However, over time, the gonococcus developed a decrease in susceptibility to the regimen used, which resulted in frank resistance to antimicrobials, progressively reducing the therapeutic options available. Thus, the study presented here aims to analyze and discuss the current scenario of resistance of N. gonorrhoeae to the antimicrobials used to date, to encourage discussion on the subject in the academic environment. For this purpose, 47 articles indexed in the Bireme, PubMed, Scielo and UpToDate platforms were selected.
Databáze: OpenAIRE