Cure of Trypanosoma musculi infection by heat-labile activity in immune plasma
| Autor: | P. A. L. Kongshavn, D. S. Wechsler |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Hot Temperature
Ratón Immunology Parasitemia Immunoglobulin E Microbiology Mice Immune system Trypanosomiasis Blood plasma parasitic diseases medicine Animals Antiserum biology Immune Sera Immunization Passive biology.organism_classification medicine.disease Mice Inbred C57BL Infectious Diseases biology.protein Trypanosoma Parasitology Immunotherapy Antibody Research Article |
| Zdroj: | Infection and immunity. 44(3) |
| ISSN: | 0019-9567 |
| Popis: | Passive transfer of plasma from a mouse cured of parasitemia to a Trypanosoma musculi-infected host rapidly eliminates parasitemia; this curative activity, presumably mediated by an immunoglobulin, is sensitive to heat treatment (56 degrees C, 30 min). In addition, pretreatment with immune plasma, even after heat treatment, prevents the development of a patent parasitemia in a naive host (protective activity). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|