Methamphetamine-Associated Heart Failure Hospitalizations Across the United States: Geographic and Social Disparities
| Autor: | Laith Alshawabkeh, Isac C. Thomas, Tuo Lin, Stephen D. Dickson, Barry H. Greenberg, Harpreet S Bhatia, Marin Nishimura, Xin M Tu, Eric Adler, Ehtisham Mahmud |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Time Factors Databases Factual Social Determinants of Health heart failure Cardiorespiratory Medicine and Haematology Cardiovascular Methamphetamine Substance Misuse Risk Factors Prevalence 80 and over Original Research Aged 80 and over alcohol Substance Abuse Middle Aged cardiac hospitalization Health Services Substance abuse Hospitalization Heart Disease Female Cardiology and Cardiovascular Medicine medicine.drug Adult medicine.medical_specialty Adolescent Amphetamine-Related Disorders Clinical Trials and Supportive Activities cardiotoxicity cocaine Risk Assessment Databases Young Adult Clinical Research Hospital discharge medicine Humans West coast Factual Aged Heart Failure Inpatients business.industry Public health Secondary diagnosis Health Status Disparities medicine.disease United States Cross-Sectional Studies Good Health and Well Being Socioeconomic Factors Heart failure Central Nervous System Stimulants business Medicaid Demography |
| Zdroj: | Journal of the American Heart Association, vol 10, iss 16 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Popis: | Background Although methamphetamine abuse is associated with the development of heart failure (HF), nationwide data on methamphetamine‐associated HF (MethHF) hospitalizations are limited. This study evaluates nationwide HF hospitalizations associated with substance abuse to better understand MethHF prevalence trends and the clinical characteristics of those patients. Methods and Results This cross‐sectional period‐prevalence study used hospital discharge data from the National Inpatient Sample to identify adult primary HF hospitalizations with a secondary diagnosis of abuse of methamphetamines, cocaine, or alcohol in the United States from 2002 to 2014. All 2014 MethHF admissions were separated by regional census division to evaluate geographical distribution. Demographics, payer information, and clinical characteristics of MethHF hospitalizations were compared with all other HF hospitalizations. Total nationwide MethHF hospitalizations increased from 547 in 2002 to 6625 in 2014 with a predominance on the West Coast. Methamphetamine abuse was slightly more common among primary HF hospitalizations compared with all‐cause hospitalizations (7.4 versus 6.4 per 1000; Cohen h= 0.012; P< 0.001). Among HF hospitalizations, patients with MethHF were younger (mean age, 48.9 versus 72.4 years; Cohen d= 1.93; P< 0.001), more likely to be on Medicaid (59.4% versus 8.8%; Cohen h= 1.16; P< 0.001) or uninsured (12.0% versus 2.6%; Cohen h= 0.36; P< 0.001), and more likely to present to urban hospitals (43.8% versus 28.3%; Cohen h= 0.32 ; P< 0.001) than patients with non‐methamphetamine associated HF. Patients with MethHF had higher rates of psychiatric comorbidities and were more likely to leave the hospital against medical advice. Conclusions MethHF hospitalizations have significantly increased in the United States, particularly on the West Coast. Coordinated public health policies and systems of care are needed to address this rising epidemic. |
| Databáze: | OpenAIRE |
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