Ethanol ablation for ventricular arrhythmias: A systematic review and meta‐analysis

Autor: Antonio Creta, Mark J. Earley, Richard J. Schilling, Malcolm Finlay, Simon Sporton, Mehul Dhinoja, Ross J. Hunter, Nikolaos Papageorgiou, Richard Ang, Anthony Chow, Martin Lowe, Oliver R. Segal, Pier D. Lambiase, Rui Providência
Rok vydání: 2022
Předmět:
Zdroj: Journal of Cardiovascular Electrophysiology. 33:510-526
ISSN: 1540-8167
1045-3873
DOI: 10.1111/jce.15336
Popis: Ethanol ablation (EA) is an alternative option for subjects with ventricular arrhythmias (VAs) refractory to conventional medical and ablative treatment. However, data on the efficacy and safety of EA remain sparse.A systematic literature search was conducted. The primary outcomes were 1) freedom from the targeted VA and 2) freedom from any VAs post-EA. Additional safety outcomes were also analyzed.Ten studies were selected accounting for a population of 174 patients (62.3 ± 12.5 years, 94% male) undergoing 185 procedures. The overall acute success rate of EA was 72.4% (confidence interval [CIEA is a valuable therapeutic option for VAs refractory to conventional treatment and can result in 1-year freedom from VA recurrence in 60%-75% of the patients. However, anatomical or technical challenges preclude acute success in almost 30% of the candidates and the rate of complication is not insignificant, highlighting the importance of well-informed patient selection. The certainty of the evidence is low, and further research is necessary.
Databáze: OpenAIRE
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