Atypical Presentation of Adrenocortical Insufficiency with Anorexia and Jaundice
Autor: | Zhen-Yu Wang, Guang-Jian Chen, Jie Liu, You-Lian Chen, Xiu-Qing Wei, Jun-Jun Zhu, Xiang-Xing Li, Yun-Wei Guo |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Pediatrics
medicine.medical_specialty medicine.drug_class Vomiting Jaundice Anorexia Alacrima 03 medical and health sciences 0302 clinical medicine medicine Adrenal insufficiency Humans Hernia 030212 general & internal medicine Diagnostic Errors Child Adrenocortical Insufficiency Glucocorticoids Aged business.industry Nausea General Medicine Articles medicine.disease Corticosteroid 030211 gastroenterology & hepatology Female medicine.symptom business Adrenal Insufficiency |
Zdroj: | The American Journal of Case Reports |
ISSN: | 1941-5923 |
Popis: | Patient: Female, 65 Final Diagnosis: Adrenocortical insufficiency Symptoms: Anorexia and jaundice Medication: Glucocorticoid replacement Clinical Procedure: — Specialty: Gastroenterology and Hepatology Objective: Challenging differential diagnosis Background: Adrenal insufficiency is mainly due to insufficient adrenal corticosteroid hormones secretion by the adrenal cortex, which leads to clinical manifestations such as weakness, weight loss, hyperpigmentation, hypotension, and vomiting. However, the clinical manifestations of adrenocortical insufficiency may be atypical: anorexia, ascites, impaired liver function, and alacrima have been reported. Jaundice and anorexia presenting together in the same patient as the main symptoms are rare. Case Report: We present a rare case of a 65-year-old woman diagnosed as having adrenocortical insufficiency with chief complaints of anorexia and jaundice. The patient had a history of hiatus hernia and gastroesophageal reflux disease, which can easily lead to a misdiagnosis in clinical practice, which is what happened with this patient at the beginning in our hospital and in the other hospitals that treated her previously. Hiatus hernia was considered the mostly likely cause of her vomiting, and a laparotomy was done to repair the hernia at the local hospital. However, there was no improvement. After regular glucocorticoid replacement, the patient’s symptoms all soon disappeared. Conclusions: Adrenal insufficiency can atypically present as anorexia and jaundice. In order to avoid misdiagnosis, physicians should pay attention to these atypical symptoms. |
Databáze: | OpenAIRE |
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