Staphylococcus aureusandStreptococcus pneumoniaeinteraction and response to pneumococcal vaccination: Myth or reality?
| Autor: | Aylana Reiss-Mandel, Gili Regev-Yochay |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Staphylococcus aureus 030106 microbiology Immunology Reviews Negative association Biology medicine.disease_cause Staphylococcal infections Pneumococcal Infections Microbiology Pneumococcal Vaccines 03 medical and health sciences Nasopharynx Antibiosis Streptococcus pneumoniae medicine Humans Immunology and Allergy Pharmacology Microbiota Infant Hydrogen Peroxide Staphylococcal Infections medicine.disease respiratory tract diseases Pneumococcal infections Carriage Child Preschool Carrier State Pneumococcal vaccination |
| Zdroj: | Human Vaccines & Immunotherapeutics. 12:351-357 |
| ISSN: | 2164-554X 2164-5515 |
| Popis: | S. aureus and S. pneumoniae are both common pathogens that are also carried by a large proportion of healthy individuals in the nasal and nasopharyngeal spaces. A negative association between carriage of S. aureus and S. pneumoniae has been reported in children in various epidemiologic studies from different geographical regions. Most studies found that the negative association between S. pneumoniae and S. aureus was significant only for carriage of vaccine-type S. pneumoniae strains. In this review, we summarize the various suggested mechanisms of this suggested bacterial interference, and the clinical implications reported following PCV introduction to date in various geographical regions. |
| Databáze: | OpenAIRE |
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