Intraperitoneal Cholelithiasis after Laparoscopic Cholecystectomy-Behavior of ‘Lost’ Concrements and Their Role in Abscess Formation
| Autor: | W. Feigl, G. Bittermann, H. Siegl, Pernegger C, H. Reckendorfer, Keiler A, R. Tessadri, S. Wenzl, G. Brinninger, Hornof R, Udo Losert |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Peritoneal Diseases Rats Sprague-Dawley Peritoneal cavity X-Ray Diffraction Cholelithiasis medicine Animals Humans Cholecystectomy Abscess Laparoscopic cholecystectomy business.industry General surgery Gallstones medicine.disease Rats Surgery Microscopy Electron Cholesterol Biliary stone medicine.anatomical_structure Abdomen Female Laparoscopy business Complication |
| Zdroj: | European Surgical Research. 28:179-189 |
| ISSN: | 1421-9921 0014-312X |
| DOI: | 10.1159/000129456 |
| Popis: | In two experimental studies we sought preliminary information about the behavior of concrements lost in the peritoneal cavity during laparoscopic cholecystectomy.In study 1, human gallstones were analyzed using X-ray diffraction, classified in three groups and examined with an ultramicroscope; then they were implanted in the peritoneal cavity of rats. After 8 weeks or 6 months, the animals were sacrificed and the concrements analyzed again as before. The tissues surrounding the calculi were also examined histologically. In study 2, human gallstones were examined with regard to bacterial contamination on the surface or in the middle of the calculi. The cholesterol content was analyzed, and the stones were divided into three groups and implantated in the rats as in the first study. After 8 weeks, the animals were sacrificed and areas with identifiable tissue reactions were examined histologically and microbiologically.The concrements lost their crystalline formation without any relation to their former cholesterol content, as shown by X-ray diffraction as well as ultramicroscopy. Mineralogically, these changes are a certain sign of structural dissolution. Cholesterol stones only caused abscess formations in association with gram-negative bowel germs. Sterile pigment concrements often led to a mesenchymal reaction such as granulomas. Contaminated pigment stones also resulted in extensive abscess formations. |
| Databáze: | OpenAIRE |
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