Corrigendum to: Epidemiological characteristics of patients with severe COVID-19 infection in Wuhan, China: evidence from a retrospective, observational study
| Autor: | Keyang Liu, Ehab S. Eshak, Zixin Zeng, Haoyu Wen, Jianjun Bai, Yong Yu, Fang Shi, Sumaira Mubarik, Jinhong Cao, Chuanhua Yu, Fang Wang, Jianbo Ding |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty China Epidemiology Respiratory Tract Diseases Disease Comorbidity Real-Time Polymerase Chain Reaction Internal medicine Diabetes mellitus medicine Humans AcademicSubjects/MED00860 Pandemics Aged Retrospective Studies business.industry SARS-CoV-2 Hazard ratio Respiratory disease COVID-19 Retrospective cohort study General Medicine Odds ratio Middle Aged medicine.disease Pneumonia Intensive Care Units Treatment Outcome Diabetes Mellitus Type 2 Cardiovascular Diseases Hypertension Female business Corrigendum |
| Zdroj: | International Journal of Epidemiology |
| ISSN: | 1464-3685 0300-5771 |
| Popis: | Background The new coronavirus (COVID-19) rapidly resulted in a pandemic. We report the characteristics of patients with severe or critical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Wuhan city, China, and the risk factors related to infection severity and death. Methods We extracted the demographic and clinical data of 7283 patients with severe COVID-19 infection from designated Wuhan hospitals as of 25 February 2020. Factors associated with COVID-19 critical illness and mortality were analysed using logistic- and Cox-regression analyses. Results We studied 6269 patients with severe COVID-19 illness and 1014 critically ill patients. The median (IQR) age was 64 (53-71) years; 51.2% were male, 38.9% were retirees and 7.4% had self-reported histories of chronic disease. Up to the end of the study, 1180 patients (16.2%) recovered and were discharged, 649 (8.9%) died and the remainder were still receiving treatment. The number of daily confirmed critical cases peaked between 23 January and 1 February 2020. Patients with advanced age [odds ratio (OR), 1.03; 95% confidence intervals (CIs), 1.03-1.04], male sex (OR, 1.57; 95% CI, 1.33-1.86) and pre-existing diabetes (OR, 2.11), hypertension (OR, 2.72), cardiovascular disease (OR, 2.15) or respiratory disease (OR, 3.50) were more likely to be critically ill. Compared with those who recovered and were discharged, patients who died were older [hazard ratio (HR), 1.04; 95% CI, 1.03-1.05], more likely to be male (HR, 1.74; 95% CI, 1.44-2.11) and more likely to have hypertension (HR, 5.58), cardiovascular disease (HR, 1.83) or diabetes (HR, 1.67). Conclusion Advanced age, male sex and a history of chronic disease were associated with COVID-19 critical illness and death. Identifying these risk factors could help in the clinical monitoring of susceptible populations. |
| Databáze: | OpenAIRE |
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