Discovery of VHR Phosphatase Inhibitors with Micromolar Activity based on Structure-Based Virtual Screening
| Autor: | Seong Eon Ryu, Dae Gwin Jeong, Seung Jun Kim, Suk-Kyeong Jung, Hwangseo Park |
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| Rok vydání: | 2008 |
| Předmět: |
Models
Molecular Phosphatase Drug Evaluation Preclinical Crystallography X-Ray Ligands Biochemistry Dual Specificity Phosphatase 3 Small Molecule Libraries Structure-Activity Relationship Drug Discovery Structure–activity relationship Computer Simulation Enzyme Inhibitors General Pharmacology Toxicology and Pharmaceutics Pharmacology Virtual screening Binding Sites Molecular Structure biology Chemistry Organic Chemistry Hydrogen Bonding Docking (molecular) Enzyme inhibitor biology.protein Molecular Medicine Structure based |
| Zdroj: | ChemMedChem. 3:877-880 |
| ISSN: | 1860-7187 1860-7179 |
| DOI: | 10.1002/cmdc.200700348 |
| Databáze: | OpenAIRE |
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