Lipid composition of myelin in multiple sclerosis
| Autor: | H. Hirono, J. F. Mead, Mona E. Fewster |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Multiple Sclerosis
Lipid composition White matter Myelin Fatty aldehyde Cerebrosides medicine Humans Myelin Sheath Phospholipids Chemistry Phosphatidylethanolamines Multiple sclerosis Fatty Acids medicine.disease Lipids Sphingolipid Sphingomyelins medicine.anatomical_structure Neurology Biochemistry Lipid content Phosphatidylcholines lipids (amino acids peptides and proteins) Cholesterol Esters Neurology (clinical) Fatty acid composition |
| Zdroj: | Journal of Neurology. 213:119-131 |
| ISSN: | 1432-1459 0340-5354 |
| DOI: | 10.1007/bf00313273 |
| Popis: | Myelin was isolated from histologically normal white matter and plaques from MS patients and from white matter of neurologically normal controls. No difference was found in the total lipid content. There were no detectable deficits in MS myelin of phosphoglycerides, plasmalogens or sphingolipids. Gangliosides and lysolecithin were not detected. Analysis of the fatty aldehyde composition of the phosphoglycerides and the fatty acid composition of the cholesteryl esters, phosphoglycerides and sphingolipids did not show any differences between the normal and MS myelin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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