The fine-scale genetic structure of the malaria vectors Anopheles funestus and Anopheles gambiae (Diptera: Culicidae) in the north-eastern part of Tanzania

Autor: Willem Takken, Pauline Gelin, Stephen M. Magesa, Caroline Maxwell, H. Magalon, Chris Drakeley, Christophe Boëte
Přispěvatelé: BOETE, Christophe, Ecologie marine tropicale dans les Océans Pacifique et Indien (ENTROPIE [Réunion]), Institut de Recherche pour le Développement (IRD)-Université de La Réunion (UR)-Centre National de la Recherche Scientifique (CNRS), Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine (LSHTM), Joint Malaria Programme, Université Paris Diderot - Paris 7 (UPD7), Amani Medical Research Centre, National Institute for Medical Research [Tanzania] (NIMR), Laboratory of Entomology, Wageningen University and Research [Wageningen] (WUR), Emergence des Pathologies Virales (EPV), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS)-Université de La Réunion (UR)-Institut de Recherche pour le Développement (IRD), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)
Jazyk: angličtina
Rok vydání: 2016
Předmět:
0301 basic medicine
Anopheles gambiae
Population genetics
spread
lowland
global warming
Tanzania
Gene flow
mosquito control
Mosquito
Laboratory of Entomology
highland
2. Zero hunger
education.field_of_study
biology
Ecology
Cline (biology)
PE&RC
3. Good health
Mosquito control
Genetic structure
ecology
altitude
microsatellite
Population
malaria
vector control
[SDV.GEN.GA] Life Sciences [q-bio]/Genetics/Animal genetics
entomology
resistance
Anopheles funestus
03 medical and health sciences
016-3966
parasitic diseases
Anopheles
medicine
education
Ecology
Evolution
Behavior and Systematics
[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]
population genetics
15. Life on land
biology.organism_classification
medicine.disease
Laboratorium voor Entomologie
populations
Malaria
[SDE.BE] Environmental Sciences/Biodiversity and Ecology
[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics
030104 developmental biology
Insect Science
[SDV.GEN.GPO] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]
insect
[SDE.BE]Environmental Sciences/Biodiversity and Ecology
cline
Zdroj: International Journal of Tropical Insect Science 36 (2016) 4
International Journal of Tropical Insect Science
International Journal of Tropical Insect Science, 2016, ⟨10.1017/S1742758416000175⟩
International Journal of Tropical Insect Science, Cambridge University Press (CUP), 2016, ⟨10.1017/S1742758416000175⟩
International Journal of Tropical Insect Science, 36(4), 161-170
ISSN: 1742-7584
DOI: 10.1017/S1742758416000175⟩
Popis: Understanding the impact of altitude and ecological heterogeneity at a fine scale on the populations of malaria vectors is essential to better understand and anticipate eventual epidemiological changes. It could help to evaluate the spread of alleles conferring resistance to insecticides and also determine any increased entomological risk of transmission in highlands due to global warming. We used microsatellite markers to measure the effect of altitude and distance on the population genetic structure ofAnopheles funestusandAnopheles gambiae s.s. in the Muheza area in the north-eastern part of Tanzania (seven loci for each species). Our analysis reveals strong gene flow between the different populations ofAn. funestusfrom lowland and highland areas, as well as between populations ofAn. gambiaesampled in the lowland area. These results highlight forAn. funestusthe absence of a significant spatial subpopulation structuring at small-scale, despite a steep ecological and altitudinal cline. Our findings are important in the understanding of the possible spread of alleles conferring insecticide resistance through mosquito populations. Such information is essential for vector control programmes to avoid the rapid spread and fixation of resistance in mosquito populations.
Databáze: OpenAIRE
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