Can Ultrasound Elastography Help Better Manage Mammographic BI-RADS Category 4 Breast Lesions?
| Autor: | Bao-Ming Luo, Yang Gu, Qi Zhou, Wu Chen, Jia-Wei Tian, Weiwei Zhan, Wei-Dong Ren, Yuxin Jiang, Hui Wang, Chun-Quan Zhang, Cai Chang, Jin-Feng Xu, Hongyan Wang, En-Sheng Xue, Jian-Jun Yuan, Man Chen, Ping Zhou, You-Bin Deng, Ying Gu, Chunsong Kang, Yu-Hong Zhang, Jianchu Li, Sheng-Lan Guo, Haitao Ran, Qing Zhou, Jie Li |
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| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty Strain elastography medicine.diagnostic_test Breast imaging business.industry Biopsy BI-RADS Breast Neoplasms Gold standard (test) Conventional ultrasound medicine.disease Breast cancer Oncology medicine Ultrasound elastography Mammography Elasticity Imaging Techniques Humans Female Radiology Ultrasonography Mammary business Retrospective Studies |
| Zdroj: | Clinical breast cancer. 22(4) |
| ISSN: | 1938-0666 |
| Popis: | Objective To assess the performance of conventional ultrasound (US) combined with strain elastography (SE) in the Breast Imaging Reporting and Data System (BI-RADS) category 4 lesions on mammography. Methods Women with breast lesions identified as having mammography BI-RADS 4 lesions and underwent US examination were included in China. US features and US BI-RADS assessment were recorded in real-time and prospectively reported. The pathological result was referred to as the gold standard. The performance of US in the mammographic BI-RADS category 4 lesions was evaluated. Diagnostic performances of US BI-RADS, SE and combined both were compared. Results 751 women with 751 breast lesions classified as mammographic BI-RADS category 4 were included. For mammographic findings, 530 (70.6%) were true-positive and 221 (29.4%) were false-positive. Conventional US achieved higher positive predictive value (PPV) than mammography (78.5% vs 70.6%, p=0.001). The specificity increased from 34.4% to 47.1% (p Conclusions Conventional US combined with SE is a helpful tool for the non-invasive examination of breast lesions classified as BI-RADS category 4 on mammography. It helped increase the PPV and had the potential to avoid unnecessary biopsies of BI-RADS category 4 lesions detected on mammography. Micro Abstract We assessed the performance of conventional ultrasound (US) combined with strain elastography (SE) in the Breast Imaging Reporting and Data System (BI-RADS) category 4 lesions on mammography. 751 women with 751 breast lesions classified as mammographic BI-RADS category 4 were included. Conventional US combined with SE helped increase the PPV and had the potential to avoid unnecessary biopsies of BI-RADS category 4 lesions detected on mammography. |
| Databáze: | OpenAIRE |
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