Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder
| Autor: | Toshio Munesue, Gerard B. Remijn, Manabu Oi, Hirotoshi Hiraishi, Yoshio Minabe, Tetsuya Takahashi, Haruhiro Higashida, Chiaki Hasegawa, Mitsuru Kikuchi, Yuko Yoshimura |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Central Auditory Processing Disorder
medicine.medical_specialty Cognitive Neuroscience Young children Audiology lcsh:Computer applications to medicine. Medical informatics behavioral disciplines and activities lcsh:RC346-429 050105 experimental psychology Lateralization of brain function Developmental psychology Correlation 03 medical and health sciences 0302 clinical medicine mental disorders medicine Magnetoencephalography (MEG) Attention deficit hyperactivity disorder 0501 psychology and cognitive sciences Radiology Nuclear Medicine and imaging lcsh:Neurology. Diseases of the nervous system medicine.diagnostic_test 05 social sciences P1m Magnetoencephalography medicine.disease Autism spectrum disorder (ASD) Comorbidity Hyperactivity Neurology Autism spectrum disorder lcsh:R858-859.7 Autism Neurology (clinical) Psychology 030217 neurology & neurosurgery |
| Zdroj: | NeuroImage: Clinical, Vol 12, Iss C, Pp 300-305 (2016) |
| ISSN: | 2213-1582 |
| DOI: | 10.1016/j.nicl.2016.07.009 |
| Popis: | The auditory-evoked P1m, recorded by magnetoencephalography, reflects a central auditory processing ability in human children. One recent study revealed that asynchrony of P1m between the right and left hemispheres reflected a central auditory processing disorder (i.e., attention deficit hyperactivity disorder, ADHD) in children. However, to date, the relationship between auditory P1m right-left hemispheric synchronization and the comorbidity of hyperactivity in children with autism spectrum disorder (ASD) is unknown. In this study, based on a previous report of an asynchrony of P1m in children with ADHD, to clarify whether the P1m right-left hemispheric synchronization is related to the symptom of hyperactivity in children with ASD, we investigated the relationship between voice-evoked P1m right-left hemispheric synchronization and hyperactivity in children with ASD. In addition to synchronization, we investigated the right-left hemispheric lateralization. Our findings failed to demonstrate significant differences in these values between ASD children with and without the symptom of hyperactivity, which was evaluated using the Autism Diagnostic Observational Schedule, Generic (ADOS-G) subscale. However, there was a significant correlation between the degrees of hemispheric synchronization and the ability to keep still during 12-minute MEG recording periods. Our results also suggested that asynchrony in the bilateral brain auditory processing system is associated with ADHD-like symptoms in children with ASD. |
| Databáze: | OpenAIRE |
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