Effects of diffuse pleural thickening on respiratory mechanics

Autor:	P A, Corris, J J, Best, G J, Gibson
Rok vydání:	1988
Předmět:	Adult Pulmonary and Respiratory Medicine Pulmonary Gas Exchange Spirometry Respiration Humans Middle Aged Pleural Diseases Lung Volume Measurements Tomography X-Ray Computed Lung Compliance Aged
Zdroj:	European Respiratory Journal. 1:248-252
ISSN:	1399-3003 0903-1936
DOI:	10.1183/09031936.93.01030248
Popis:	Five patients with radiographic and computed tomography (CT) evidence of extensive pleural thickening were studied. All had a restrictive ventilatory defect. The single breath carbon monoxide transfer factor (TLCO) was reduced in each case (mean 76% predicted) but in four patients the transfer coefficient (KCO) was increased (mean 116% predicted), which is consistent with lung 'en cuirasse'. Static pressure-volume curves of the lungs showed that the maximum transpulmonary pressure was greater than normal and pulmonary compliance was reduced; the curves were therefore indistinguishable from those obtained in patients with pulmonary fibrosis. Transdiaphragmatic pressures during maximal inspiratory efforts were moderately impaired and the proportions of each tidal breath contributed by anterposterior (AP) motion of rib cage and abdomen were similar to normal in both erect and supine postures, suggesting that diaphragmatic mobility was well preserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1c0dbab3ec5c1539331ed6dd67a00c https://doi.org/10.1183/09031936.93.01030248 Zobrazit plný text záznamu