Relationship between the Diabetic Polyneuropathy Index and the Neurological Findings of Diabetic Polyneuropathy
| Autor: | Katsumi Kurokawa, Taiji Nagai, Akio Asano, Yoshihide Sunada, Tatsufumi Murakami, Masahito Mihara, Toshio Okamoto, Shoji Hemmi, Keiichi Yokoi |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Coefficient of variation Neural Conduction 030204 cardiovascular system & hematology Gastroenterology Sensitivity and Specificity Severity of Illness Index F wave 03 medical and health sciences Young Adult 0302 clinical medicine Diabetic Neuropathies Diabetic polyneuropathy Internal medicine Diabetes mellitus Internal Medicine medicine Humans Neurological findings Aged Retrospective Studies Aged 80 and over sensory nerve conduction velocity diabetes business.industry F wave minimum latency General Medicine Middle Aged diabetic polyneuropathy index medicine.disease compound muscle action potential Compound muscle action potential 030211 gastroenterology & hepatology Female Original Article sensory nerve action potential Abnormality business Sensory nerve conduction velocity |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 |
| Popis: | Objective To achieve an accurate quantification in diabetic polyneuropathy (DPN), we developed a new electrophysiological index that we called the DPN index. The relationship between the DPN index and the neurological findings in diabetic patients was assessed. Methods The DPN index was calculated by the mean value of percentages of four parameters (tibial compound muscle action potential amplitude / F wave minimum latency, sural sensory nerve action potential amplitude / sensory nerve conduction velocity) against the mean normal values. Twenty healthy subjects were recruited as a control group. Patients A total of 348 diabetic patients who were hospitalized in our hospital during the period from December 2016 to August 2019 were retrospectively studied. The correlations between the DPN index and five neurological findings (subjective sensory symptoms, diminished or absent Achilles tendon reflex, impaired tactile and vibration sense, low coefficient of variation of R-R interval) were evaluated. Results The DPN index in healthy subjects was 129.3±32.7%. The DPN index in diabetic patients with one or more neurological findings was significantly lower than that in diabetic patients without any neurological findings (p |
| Databáze: | OpenAIRE |
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