Respiratory resistance among adults in a population-based cohort study in Northern Japan
| Autor: | Ritsuko Arakawa, Masao Tabata, Etsuhiro Nikkuni, Yoichi Suzuki, Shinichi Kuriyama, Shinya Ohkouchi, Toshiya Irokawa, Yu Igarashi, Masayuki Yamamoto, Emiri Miura, Tokiwa Tamai, Naho Tsuchiya, Hajime Kurosawa, Hiromasa Ogawa, Gen Tamiya, Takako Takai-Igarashi, Atsushi Hozawa |
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| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male medicine.medical_specialty Body Mass Index Cohort Studies Leukocyte Count Young Adult Forced Oscillation Technique Japan Internal medicine medicine Humans Young adult Respiratory system Aged Aged 80 and over Sex Characteristics business.industry Airway Resistance Respiration Smoking Immunoglobulin E Middle Aged medicine.disease Obesity Body Height Respiratory Function Tests Eosinophils Cohort Female business Body mass index Cohort study Sex characteristics |
| Zdroj: | Respiratory investigation. 57(3) |
| ISSN: | 2212-5353 |
| Popis: | Background Forced oscillation technique (FOT) is a noninvasive method used to measure respiratory system resistance (Rrs) and reactance (Xrs) during quiet breathing, which has been extensively studied in clinical settings. The distribution of measured FOT values was previously assessed in a community-based cohort study. In this study, we aimed to confirm the distribution of measured FOT values in a different cohort in order to investigate the relationship between these values and patient clinical and biological data. Methods We reviewed FOT data and relevant patient clinical and biological information collected from the Community-Based Cohort Study (CommCohort Study), carried out between 2013 to 2016 as a part of the Tohoku Medical Megabank project (TMM). In total, 16,231 adults were enrolled in the study (Male/Female: 4886/11,345). Results Significant gender differences were observed in distributions of Rrs and Xrs values at 5 Hz (termed R5 and X5, respectively). R5 values in males were lower than those in females, while X5 values in males were slightly less negative. High R5 values were strongly associated with high BMI, short height, smoking status in males, high serum IgE level, and high peripheral blood eosinophil count. Conclusion The present distribution values and their relation to clinical and biological data should provide useful insights for clinical settings and serve as a helpful guide in implementing FOT. Forced oscillation technique, respiratory system resistance, respiratory system reactance, gender difference, obesity. |
| Databáze: | OpenAIRE |
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