Circulating tumor cells in germ cell tumors: are those biomarkers of real prognostic value? A review
| Autor: | Rares Buiga, Nicoleta Zenovia Antone, Cristina Ligia Cebotaru, Viorica Nagy, Elena Diana Olteanu |
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| Rok vydání: | 2016 |
| Předmět: |
Oncology
Metastatic breast medicine.medical_specialty Prognostic factor biomarkers Cancer Review General Medicine circulating tumor cells Biology medicine.disease_cause medicine.disease Metastasis Prostate cancer Circulating tumor cell Internal medicine medicine Germ cell tumors germ cell tumors Carcinogenesis |
| Zdroj: | Clujul Medical |
| ISSN: | 2668-0572 2602-0807 |
| Popis: | Analysis of circulating tumor cells from patients with different types of cancer is nowadays a fascinating new tool of research and their number is proven to be useful as a prognostic factor in metastatic breast, colon, and prostate patients. Studies are going beyond enumeration, exploring the circulating tumor cells to better understand the mechanisms of tumorigenesis, invasion, and metastasis and their value for characterization, prognosis and tailoring of treatment. Few studies investigated the prognostic significance of circulating tumor cells in germ cell tumors. In this review, we examine the possible significance of the detection of circulating tumor cells in this setting. |
| Databáze: | OpenAIRE |
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